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Research Spending & Results

Award Detail

Awardee:LOUISIANA STATE UNIVERSITY
Doing Business As Name:Louisiana State University
PD/PI:
  • Slawomir M Lomnicki
  • (225) 578-8147
  • slomni1@lsu.edu
Co-PD(s)/co-PI(s):
  • Phillip T Sprunger
  • Dorin Boldor Dr/
  • Lavrent Khachatryan
  • Krisztian Stadler
Award Date:07/29/2021
Estimated Total Award Amount: $ 1,462,820
Funds Obligated to Date: $ 1,462,820
  • FY 2021=$1,462,820
Start Date:08/01/2021
End Date:07/31/2023
Transaction Type:Grant
Agency:NSF
Awarding Agency Code:4900
Funding Agency Code:4900
CFDA Number:47.041
Primary Program Source:040100 NSF RESEARCH & RELATED ACTIVIT
Award Title or Description:MRI: Acquisition of High Frequency Electron Paramagnetic Spectrometer – cutting edge tool for modern research
Federal Award ID Number:2117638
DUNS ID:075050765
Parent DUNS ID:940050792
Program:Major Research Instrumentation
Program Officer:
  • Shahab Shojaei-Zadeh
  • (703) 292-8045
  • sshojaei@nsf.gov

Awardee Location

Street:202 Himes Hall
City:Baton Rouge
State:LA
ZIP:70803-2701
County:Baton Rouge
Country:US
Awardee Cong. District:06

Primary Place of Performance

Organization Name:Louisiana State University
Street:Dept. Environmental Sciences
City:Baton Rouge
State:LA
ZIP:70803-2701
County:Baton Rouge
Country:US
Cong. District:06

Abstract at Time of Award

This award enables the acquisition of the most modern instrumentation (high frequency/high field electron paramagnetic spectrometer) to study structure of compounds that contain unpaired electrons. Such molecules are called “paramagnetic” and have critical functions in living organisms and in the environment. This instrument will provide a cutting edge tool for studies in medicine and biology (new drug development, understanding of protein activity and interactions, and development of new molecules used for disease diagnostics), informatics and engineering (development of new class of memory chips, green energy materials) and will allow for significant technological jump that enables advanced studies of such systems. Studies of paramagnetic compounds have been hampered due to poor resolution of existing technology and this technique has not traditionally been used as a common tool for research due to its technological limitations and low availability. This instrument will not only add a completely new dimension to the research capabilities for many regional and national researchers, but also provide an essential learning tool for a new generation of scientists. Training will be provided to students and postdoctoral associates nationwide through an open house program advertised at research institutions throughout the country. The award seeks to purchase the Bruker ELEXYS E780, the first commercially manufactured high frequency/high field electron paramagnetic spectrometer in the United States, operating at 263 GHz. This would be the second instrument operating above 250 GHz; and the only high frequency instrument with electron-nuclear resonance capabilities. The ELEXYS E780 can perform experiments at both continuous wave and pulse wave mode, with electron-nuclear double resonance and electron-nuclear-nuclear resonance techniques and at temperatures down to 4 K. As a result, a significant increase in sensitivity and resolution of the spin orientation in the magnetic field can be achieved, which provides detailed structural information of the paramagnetic center. Detailed information regarding the nuclear distances from the paramagnetic centers and high spectral resolution can be achieved in solids, gases, liquids, cells, and in vivo. Projects that will immediately benefit from the acquisition of this instrument include research to understand changes in mitochondria function in diseases; photosystem II operation and development of man-made photosynthesis systems; conversion of biomass into valuable products; engineering of better polymers; development of new bioimaging molecules; and understanding the origin and fate of many environmental pollutants. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

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