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Research Spending & Results

Award Detail

Awardee:NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY
Doing Business As Name:North Carolina Agricultural & Technical State University
PD/PI:
  • Jagannathan Sankar
  • (336) 285-3221
  • sankar@ncat.edu
Co-PD(s)/co-PI(s):
  • Mark J Schulz
  • William R Wagner
Award Date:08/29/2008
Estimated Total Award Amount: $ 18,500,000
Funds Obligated to Date: $ 36,683,700
  • FY 2013=$4,002,100
  • FY 2010=$2,534,043
  • FY 2008=$3,250,000
  • FY 2012=$4,020,000
  • FY 2011=$4,000,000
  • FY 2009=$4,915,957
  • FY 2016=$4,106,000
  • FY 2014=$8,000,000
  • FY 2017=$1,835,600
  • FY 2015=$20,000
Start Date:09/01/2008
End Date:01/31/2021
Transaction Type: Cooperative Agreements
Agency:NSF
Awarding Agency Code:4900
Funding Agency Code:4900
CFDA Number:47.041
Primary Program Source:040100 NSF RESEARCH & RELATED ACTIVIT
Award Title or Description:NSF Engineering Research Center for Revolutionizing Metallic Biomaterials
Federal Award ID Number:0812348
DUNS ID:071576482
Parent DUNS ID:071576482
Program:ERC-Eng Research Centers
Program Officer:
  • Leon Esterowitz
  • (703) 292-7942
  • lesterow@nsf.gov

Awardee Location

Street:1601 E. Market Street
City:Greensboro
State:NC
ZIP:27411-0001
County:Greensboro
Country:US
Awardee Cong. District:06

Primary Place of Performance

Organization Name:North Carolina Agricultural & Technical State University
Street:1601 E. Market Street
City:Greensboro
State:NC
ZIP:27411-0001
County:Greensboro
Country:US
Cong. District:06

Publications Produced as a Result of this Research

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Lee, Dong-Hyun; Kumta, Prashant N. "Chemical synthesis and characterization of magnesium substituted amorphous calcium phosphate (MG-ACP)" Mater. Sci. Eng., C, v.30, 2010, p.1313.

Desai, Salil; Perkins, Jessica; Harrison, Benjamin S.; Sankar, Jag "Understanding release kinetics of biopolymer drug delivery microcapsules for biomedical applications" Mater. Sci. Eng., B, v.168, 2010, p.127.

Lee, Donghyun; Kumta, Prashant N. "Chemical synthesis and stabilization of magnesium substituted brushite" Mater. Sci. Eng., C, v.30, 2010, p.934.

Baldwin J Timothy; Borovetz Harvey S; Duncan Brian W; Gartner Mark J; Jarvik Robert K; Weiss William J "The national heart, lung, and blood institute pediatric circulatory support program: a summary of the 5-year experience" Circulation, v.123, 2011, p.1233.

YeoHeung Yun, Zhongyun Dong, Dianer Yang, Mark J. Schulz, Vesselin N. Shanov, Sergey Yarmolenko, Zhigang Xu, Prashant Kumta and Charles Sfeir "Biodegradable Mg corrosion and osteoblast cell culture studies" Materials Science and Engineering: C, v.29, 2009, p.1814.

Johnson Carl A Jr; Vandenberghe Stijn; Daly Amanda R; Woolley Joshua R; Snyder Shaun T; Verkaik Josiah E; Ye Sang-Ho; Borovetz Harvey S; Antaki James F; Wearden Peter D; Kameneva Marina V; Wagner William R "Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device" Artificial Organs, v.35, 2011, p.9.

Konchady, Manohar S.; Yarmolenko, Sergey; Pai, Devdas M.; Sankar, Jagannathan; Kvit, Alexander V. "Nanoscratch behaviour, structure and nanoindentation of multilayer TiN/CrN coatings" Int. J. Surf. Sci. Eng., v.2(6), 2008, p.439-456.

YeoHeung Yun, Zhongyun Dong, Zongqin Tan, Mark J. Schulz, Vesselin Shanov "Fibroblast cell behavior on chemically functionalized carbon nanomaterials" Material science and engineering: C, v.29, 2009, p.719.

Hong, Yi; Ye, Sang-Ho; Nieponice, Alejandro; Soletti, Lorenzo; Vorp, David A.; Wagner, William R. "A small diameter, fibrous vascular conduit generated from a poly(ester urethane)urea and phospholipid polymer blend" Biomaterials, v.30, 2009, p.2457.

Nguyen, Tan D.; Liang, Rui; Woo, Savio L-Y.; Burton, Shawn D.; Wu, Changfu; Almarza, Alejandro; Sacks, Michael S.; Abramowitch, Steven "Effects of Cell Seeding and Cyclic Stretch on the Fiber Remodeling in an Extracellular Matrix-Derived Bioscaffold" Tissue Eng., Part A, v.15, 2009, p.957.

Li, Jinhua; Olton, Dana; Lee, Donghyun; Kumta, Prashant N.; Sfeir, Charles. "Cell Derived Hierarchical Assembly of a Novel Phosphophoryn-Based Biomaterial" Cells Tissues Organs, v.189, 2009, p.252.

Deepthi, B.; Barshilia, Harish C.; Rajam, K. S.; Konchady, Manohar S.; Pai, Devdas M.; Sankar, Jagannathan; Kvit, Alexander V. "Structure, morphology and chemical composition of sputter deposited nanostructured Cr-WS2 solid lubricant coatings" Surf. Coat. Technol., v.205, 2010, p.565.

Luo, Xiliang; Cui, Xinyan Tracy "Electrochemically controlled release based on nanoporous conducting polymers" Electrochem. Commun., v.11, 2009, p.402.

Simon, Marc A.; Watson, John; Baldwin, J. Timothy; Wagner, William R.; Borovetz, Harvey S. "Current and future considerations in the use of mechanical circulatory support devices" Annu. Rev. Biomed. Eng., v.10, 2008, p.59 - 84.

Yun, Yeoheung; Dong, Zhongyu; Lee, Namheon; Liu, Yijun; Xue, Dingchuan; Guo, Xuefei; Kuhlmann, Julia; Doepke, Amos; Halsall, H. Brian; Heineman, William; Sundaramurthy, Surya; Schulz, Mark J.; Yin, Zhangzhang; Shanov, Vesselin; Hurd, Douglas; Nagy, Peter; "Revolutionizing biodegradable metals" Materials Today (Oxford, U. K.), v.12, 2009, p.22.

Xue, Dingchuan; Yun, Yeoheung; Schulz, Mark J.; Shanov, Vesselin. "Corrosion protection of biodegradable magnesium implants using anodization" Mater. Sci. Eng., C, v.31, 2011, p.215.

Li, Jinhua; Olton, Dana; Lee, Donghyun; Kumta, Prashant N.; Sfeir, Charles "Cell Derived Hierarchical Assembly of a Novel Phosphophoryn-Based Biomaterial" Cells Tissues Organs, v.189 (1-, 2009, p.252-255.

Yun, Yeo-Heung; Eteshola, Edward; Bhattacharya, Amit; Dong, Zhongyun; Shim, Joon-Sub; Conforti, Laura; Kim, Dogyoon; Schulz, Mark J.; Ahn, Chong H.; Watts, Nelson "Tiny medicine: nanomaterial-based biosensors" Sensors, v.9, 2009, p.9275.

Woo, Savio L.-Y.; Liang, Rui; Fisher, Matthew B. "Future of orthopaedic sports medicine and soft tissue healing: the important role of engineering" Cell. Mol. Bioeng., v.2, 2009, p.448.

Jayasinghe, Chaminda; Chakrabarti, Supriya; Schulz, Mark J.; Shanov, Vesselin "Spinning yarn from long carbon nanotube arrays" J. Mater. Res., v.26, 2011, p.645.

Lee, Donghyun; Sfeir, Charles; Kumta, Prashant N. "Novel in-situ synthesis and characterization of nanostructured magnesium substituted beta -tricalcium phosphate (beta -TCMP)" Mater. Sci. Eng., C, v.29, 2009, p.69.

Almarza Alejandro J; Augustine Serena M; Woo Savio L-Y "Changes in gene expression of matrix constituents with respect to passage of ligament and tendon fibroblasts" Ann. Biomed. Eng., v.36, 2008, p.1927.

Simon, Marc A.; Watson, John; Baldwin, J. Timothy; Wagner, William R.; Borovetz, Harvey S. "Current and future considerations in the use of mechanical circulatory support devices" Annu. Rev. Biomed. Eng., v.10, 2008, p.59.

Konchady, Manohar S.; Yarmolenko, Sergey; Pai, Devdas M.; Sankar, Jagannathan; Kvit, Alexander V. "Nanoscratch behaviour, structure and nanoindentation of multilayer TiN/CrN coatings" Int. J. Surf. Sci. Eng., v.2, 2008, p.439.

Kokai, L.E.; Ghaznavi, A.M.; Marra, K.G "Incorporation of double-walled microspheres into polymer nerve guides for the sustained delivery of glial cell line-derived neurotrophic factor" Biomaterials, v.31 (8), 2010, p.2313.

Ghaznavi, A.M.; Kokai, L.E.; Lovett, M.L.; Kaplan, D.L.; Marra, K.G. "Silk Fibroin Conduits: A Cellular and Functional Assessment of Peripheral Nerve Repair" Annals of Plastic Surgery, v.66 (3), 2011, p.273.

Sfeir, Charles; Lee, Donghyun; Li, Jinhua; Zhang, Xiaoyuan; Boskey, Adele L.; Kumta, Prashant N. "Expression of Phosphophoryn Is Sufficient for the Induction of Matrix Mineralization by Mammalian Cells" J. Biol. Chem., v.286, 2011, p.20228.

P. Slusser, D. Kumar, and A. Tiwari "Unexpected magnetic behavior of Cu-doped CeO2" Applied Physics Letters, v.96, 2010, p.142506.

Guo, Xuefei; Yun, Yeoheung; Shanov, Vesselin N.; Halsall, H. Brian; Heineman, William R. "Determination of Trace Metals by Anodic Stripping Voltammetry Using a Carbon Nanotube Tower Electrode" Electroanalysis, v.23, 2011, p.1252.

Hsu-Feng Ko, Charles Sfeir and Prashant N. Kumta "Novel Synthesis Strategies for Natural Polymer and Composite Biomaterials as Potential Scaffolds for Tissue Engineering" Philosophical Transactions A, v.368, 2010, p.1981.

Hong, Yi; Ye, Sang-Ho; Nieponice, Alejandro; Soletti, Lorenzo; Vorp, David A.; Wagner, William R. "A small diameter, fibrous vascular conduit generated from a poly(ester urethane)urea and phospholipid polymer blend" Biomaterials, v.30 (13), 2009, p.2457-2467.

Jingchun Wu, Bradley Paden, Harvey Borovetz and James Antaki "Computational Fluid Dynamics (CFD) Analysis of Blade Tip Clearances on Hemodynamic Performance and Blood Damage in a Centrifugal Ventricular Assist Device" Artificial Organs, v.34(5), 2010, p.402.

4. Antaki JF, Ricci MR, Verkaik JE, Snyder ST, Maul TM, Kim J, Paden DB, Kameneva MV, Paden BE, Wearden PD, Borovetz HS "PediaFlow Maglev Ventricular Assist Device: A Prescriptive Design Approach" Cardiovascular Engineering and Technology, v.1(1), 2010, p.104.

MM Ivancic, HS Gadgil, HB Halsall, MJ Treuheit, "LC/MS analysis of complex multiglycosylated human alpha(1)-acid glycoprotein as a model for developing identification and quantitation methods for intact glycopeptide analysis" Anal. Biochem., v.400(1), 2010, p.25.

Jurkevica A, Halsall HB, Seliskar CJ, Heineman WR. "Effect of some physico-chemical conditions on an immunoassay for viable Escherichia coli" Anal Bioanal Chem., v.397(7), 2010, p.3133.

Barshilia, Harish C.; Acharya, Shashidhara; Ghosh, Moumita; Suresh, T. N.; Rajam, K. S.; Konchady, Manohar S.; Pai, Devdas M.; Sankar, Jagannathan "Performance evaluation of TiAlCrYN nanocomposite coatings deposited using four-cathode reactive unbalanced pulsed direct current magnetron sputtering system" Vacuum, v.85, 2010, p.411.

Ko, Seonghyuk; Banerjee, Chandra K.; Sankar, Jagannathan "Photochemical synthesis and photocatalytic activity in simulated solar light of nanosized Ag doped TiO2 nanoparticle composite" Composites, Part B, v.42B, 2011, p.579.

Jayasinghe, Chaminda; Li, Weifeng; Song, Yi; Abot, Jandro L.; Shanov, Vesselin N.; Fialkova, Svitlana; Yarmolenko, Sergey; Sundaramurthy, Surya; Chen, Ying; Cho, Wondong; Chakrabarti, Supriya; Li, Ge; Yun, Yeoheung; Schulz, Mark J. "Nanotube responsive materials" MRS Bulletin, v.35, 2010, p.682.

Liang, Rui; Fisher, Matthew; Yang, Guoguang; Hall, Christine; Woo, Savio L.-Y. "Alpha1,3-galactosyltransferase knockout does not alter the properties of porcine extracellular matrix bioscaffolds" Acta Biomater., v.7, 2011, p.1719.

Deepthi, B.; Barshilia, Harish C.; Rajam, K. S.; Konchady, Manohar S.; Pai, Devdas M.; Sankar, Jagannathan "Mechanical and tribological properties of sputter deposited nanostructured Cr-WS2 solid lubricant coatings" Surf. Coat. Technol., v.205, 2010, p.1937.

Hopkins, Tracy M.; Vennemeyer, John; Jayasinghe, Chaminda; Shanov, Vesselin; Pixley, Sarah K. "Carbon nanotube ribbon and thread support attachment and differentiation of neural stem cells" Nano LIFE, v.1, 2010, p.89.

Lee, Donghyun; Sfeir, Charles; Kumta, Prashant N. "Novel in-situ synthesis and characterization of nanostructured magnesium substituted beta -tricalcium phosphate (beta -TCMP)" Mater. Sci. Eng., C, v.29 (1), 2009, p.69-77.

Luo, Xiliang; Cui, Xinyan Tracy "Electrochemically controlled release based on nanoporous conducting polymers" Electrochem. Commun., v.11 (2), 2009, p.402-404.

Hong, Yi; Guan, Jianjun; Fujimoto, Kazuro L.; Hashizume, Ryotaro; Pelinescu, Anca L.; Wagner, William R. "Tailoring the degradation kinetics of poly(ester carbonate urethane)urea thermoplastic elastomers for tissue engineering scaffolds" Biomaterials, v.31, 2010, p.4249.

Velikokhatnyi, Oleg I.; Kumta, Prashant N. "First-principles studies on alloying and simplified thermodynamic aqueous chemical stability of calcium-, zinc-, aluminum-, yttrium- and iron-doped magnesium alloys" Acta Biomater., v.6, 2010, p.1698.

Ye, Sang-Ho; Johnson, Carl A., Jr.; Woolley, Joshua R.; Murata, Hironobu; Gamble, Lara J.; Ishihara, Kazuhiko; Wagner, William R. "Simple surface modification of a titanium alloy with silanated zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity" Colloids Surf., B, v.79, 2010, p.357.

Nguyen, Tan D.; Liang, Rui; Woo, Savio L-Y.; Burton, Shawn D.; Wu, Changfu; Almarza, Alejandro; Sacks, Michael S.; Abramowitch, Steven "Effects of Cell Seeding and Cyclic Stretch on the Fiber Remodeling in an Extracellular Matrix-Derived Bioscaffold" Tissue Eng., Part A, v.15 (4), 2009, p.957-963.

Almarza Alejandro J; Augustine Serena M; Woo Savio L-Y "Changes in gene expression of matrix constituents with respect to passage of ligament and tendon fibroblasts" Ann Biomed Eng, v.36 (12), 2008, p.1927 - 19.

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